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Compound InformationSONAR Target prediction
Name:

Camptothecin

Unique Identifier:LAT002A02
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C20H16N2O4
Molecular Weight:332.225 g/mol
X log p:11.182  (online calculus)
Lipinksi Failures1
TPSA58.97
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:1
Canonical Smiles:CCC1(O)C(=O)OCC2C(=O)N3Cc4cc5ccccc5nc4C3=CC=21

Found: 1 nonactive | as graph: single | with analogs
Species: 4932
Condition: wt24h
Replicates: 2
Raw OD Value: r im 0.7700±0.0026163
Normalized OD Score: sc h 0.9439±0.00349999
Z-Score: -2.3653±0.88159
p-Value: 0.0421588
Z-Factor: 0.0333498
Fitness Defect: 3.1663
Bioactivity Statement: Nonactive
Experimental Conditions
Library:LATCA
Plate Number and Position:2|A2
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.40 Celcius
Date:2007-02-28 YYYY-MM-DD
Plate CH Control (+):0.04±0.00274
Plate DMSO Control (-):0.810125±0.01183
Plate Z-Factor:0.9322
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DBLink | Rows returned: 71 2 Next >> 
2538
24360
32939
153546
184196
10497972

internal high similarity DBLink | Rows returned: 3
LOPAC 00814 1.0000
Prest102 1.0000
SPE01502232 1.0000

active | Cluster 1530 | Additional Members: 9 | Rows returned: 5
SPE01504123 0.178082191780822
LOPAC 00814 0
SPE01502232 0
Prest102 0
LAT003C09 0

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